Azole

Composition

Albendazole USP 400mg

Indication

Azole (Albendazole) is used in the treatment of single or mixed intestinal infections caused by Enterobius vermicularis (Pinworm, Threadworm), Trichuris trichiura (Whipworm), Ascaris lumbricoides (Roundworm), Ancylostoma duodenale & Nector americanus (Hookworm), Taenia solium & Taenia saginata (Tapeworm), Strongyloides stercoralis. Albendazole is indicated in giardiasis in children over 2 years of age.

Dosage

Adults & children (over two years): Azole 400 mg (one Azole 400 tablet or 10ml Azole suspension) as a single dose in cases of Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale and Nector americanus. In cases of strongyloidiasis or taeniasis, 400 mg (one Azole 400 tablet or 10 ml Azole suspension) as a single dose should be given for three consecutive days. Giardiasis: 400 mg (one Azole 400 tablet or 10 ml Azole suspension) once daily for five days. Azole (Albendazole) in hydatid disease (Echinococcosis): In the treatment of echinococcosis, Azole (Albnedazole) is given by mouth with meals in a dose of 400 mg twice daily for 28 days for patients weighing over 60 kg. A dose of 15 mg/kg body weight daily in two divided doses (to a maximum total daily dose of 800 mg) is used for patients weighing less than 60 kg. For cystic echinicoccosis the 28 day course may be repeated after 14 days without treatment to a total of three treatment cycles. For alveolar echinococcosis, cycles of 28 days of treatment followed by 14 days without treatment may need to continue for months or years. When administering albendazole in the preor post-surgical setting, optimal killing of cyst contents is achieved when three courses of therapy have been given.